Dune is a Adventure, Strategy game published by Virgin Games released on 1992 for the MS-DOS.
How to play Dune (DOS):
The simplest way is to get Winrar and extract the package. Drag the dune.iso file into DOSBox shortcut. then type d: hit enter then type dune hit enter.
The first time you do this you'll be asked to confirm your settings. Hit enter.
Select automatic configuration, and exit. Once you see the prompt again (D:\>) type dune again and hit enter one last time. You are in!
The next time you want to play dragging the iso, typing d: and then dune will launch the game.